1. Chen Lijun#., Peng Chao #., Chai Lanyi #., Zhang Renjie #., Zhu Chenghang., Wang Hailin., Cheng Qirong., Yan Yan., Shen Cailiang., Zheng Hong., Yang Jiazhao*., Fan Haitao*., Kan Chen*. GNAS/PKA pathway promotes aberrant osteochondral differentiation of Gli1+ tendon sheath progenitors. The EMBO Journal (Nature index, 中科院一区, IF=8.3), 2025 (Accept). 最后通讯作者
2. Kan Chen*., Tan Zhenya., Wang Haitao., Wang Wei., Yang Jiazhao., Zhang Ya., Lu Xiaoling., Cheng Qirong., Chai Lanyi., Peng Chao., Zhu Jicheng., Zhu Chenghang., Wang Hailin., Zhan Li., Lin Keqiong., Liu Yakun., Zhang Lingqiang., Fan Haitao*., Zheng Hong*. Spatiotemporal analysis of mesenchymal stem cells fate determination by inflammatory niche following soft tissue injury at the single-cell level. Advanced Science(中科院一区,IF=14.3),2024,11(43):e2310282. 第一兼共同通讯作者
3. Tan Zhenya#., Pan Ke#., Sun Minqiong#., Pan Xianzhu., Yang Zhi., Chang Zhiling., Yang Xue., Zhu Jicheng., Zhan Li., Liu Yakun., Li Xiaofei., Lin Keqiong., Chen Lin., Mo Hui., Luo Wei., Kan Chen*., Duan Lunxi*., Zheng Hong*. CCKBR+ cancer cells contribute to the intratumor heterogeneity of gastric cancer and confer sensitivity to FOXO inhibition. Cell Death and Differentiation(中科院一区 TOP,IF=13.7),2024,31(10):1302-1317. 共同通讯作者
4. Kan Chen#., Tan Zhenya#., Liu Liwei#., Liu Bo., Zhan Li., Zhu Jicheng., Li Xiaofei., Lin Keqiong., Liu Jia., Yakun Liu., Yang Fan., Wong Mandy., Wang Siying*., Zheng Hong*. Phase separation of SHP2E76K promotes malignant transformation of mesenchymal stem cells by activating mitochondrial complexes. JCI Insight(中科院一区,IF=8),2024,9 (8):e170340. 第一作者
5. Kan Chen#., Yang Jiazhao#., Fan Haitao#., Dai Yuanjuan., Wang Xingxing., Chen Rui., Liu Jia., Meng Xiangyue., Wang Wei., Li Guiling., Zhou Jiao., Zhang Ya., Zhu Wanbo., Fang Shiyuan., Wei Haiming., Zheng Hong*., Wang Siying*., Ni Fang*. Fetuin-A is an immunomodulator and a potential therapeutic option in BMP4- dependent heterotopic ossification and associated bone mass loss. Bone Research(中科院一区,IF=12.7),2022,10(1):62. 第一作者
6. Kan Chen#., Yang Jiazhao#., Na Ding., Xu Yuanhong., Yang Baixia., Zhao Haodong., Lu Huadong., Li Yuyun., Zhang Keqin., McGuire Tammy L., Kessler John A*., Kan Lixin. Inhibition of immune checkpoints prevents injury-induced heterotopic ossification. Bone Research(中科院一区,IF=11.508),2019,7, 33. 第一作者
7. Zhu Guangya., Xie Jingjing., Kong Wenna., Xie Jingfei., Li Yichen., Du Lin., Zheng Qiangang., Sun Lin., Guan Mingfeng., Li Huan., Zhu Tianxin., He Hao., Liu Zhenying., Xia Xi., Kan Chen., Tao Youqi., Shen Hong C., Li Dan., Wang Siying., Yu Yongguo., Yu Zhi-Hong., Zhang Zhong-Yin., Liu Cong., Zhu Jidong. Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation. Cell(中科院一区,IF=66.85),2020,183(2), 490-502.e18. 共同作者
8. Kan Chen., Ding Na., Yang Jiazhao., Tan Zhenya., McGuire Tammy L., Lu Haimei., Zhang Keqin., Berger Diana M Palila., Kessler John A., Kan Lixin. BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification. Stem Cell Research and Therapy(中科院二区,IF=8.079),2019, 10(1), 14. 第一作者
9. Kan Chen., Chen Lijun., Hu Yangyang., Ding Na., Li Yuyun., McGuire Tammy L., Lu Haimei., Kessler John A., Kan Lixin. Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification. Bone(中科院二区,IF=4.626),2018,109, 71-79. 第一作者
10. Kan Chen., Yang Fan., Wang Siying. SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction. Stem Cells International(中科院三区,IF=5.131),2018, 8351374. 第一作者
11. Kan Chen., Chen Lijun., Hu Yangyang., Ding Na., Lu Haimei., Li Yuyun., Kessler John A., Kan Lixin. Conserved signaling pathways underlying heterotopic ossification. Bone(中科院二区,IF=4.626),2018,109, 43-48. 第一作者
12. Kan Chen., Chen Lijun., Hu Yangyang., Lu Haimei., Li Yuyun., Kessler John A., Kan Lixin.(2017). Microenvironmental factors that regulate mesenchymal stem cells: lessons learned from the study of heterotopic ossification. Histology and Histopathology(中科院四区,IF=2.13),2017, 32(10), 977-985. 第一作者
13. Kan Chen., Kan Lixin. The burning questions of heterotopic ossification. Annals of Translational Medicine(中科院四区,IF=3.616) 2015, 3(2), 14. 第一作者