沈兵，博士，1998年本科毕业于安徽医科大学临床医学专业，2003年硕士毕业于暨南大学药理学专业，2009年博士毕业于香港中文大学生理系并于同年人才引进加入安徽医科大学生理教研室，先后在香港中文大学、香港大学、美国德克萨斯大学休斯顿健康科学中心进行博士后研究，现任安徽医科大学生理教研室教授、博士生导师，安徽省杰出青年基金获得者，校中青年学术技术带头人。主要研究方向集中在离子通道生理病理功能及人类遗传病上。自2003年以来在Cell Research、Nature Communications、Circulation Research等国际知名SCI收录杂志发表110余篇科研成果，获得发明专利3项、两项国家自然科学基金面上项目、安徽省自然科学基金面上项目和留学回国人员等基金资助、安徽省自然科学奖三等奖。

1. 2014年1月-2017年12月（主持）：TRPP2-STIM1相互作用：脑缺血再灌注损伤新机制研究，国家自然科学基金面上项目（批准号：81371284），70万元，已结题。

2. 2016年1月 -2019年12月（主持）：内皮祖细胞外泌体在动脉内皮损伤修复和糖尿病动脉粥样硬化发生中的作用，国家自然科学基金面上项目（批准号：81570403），57万元，已结题。

3. 2012年1月-2013年12月（主持）：细胞膜生理功能研究，安徽省杰出青年基金（批准号：1108085J11），15万，已结题。

4. 2021年1月-2023年12月（主持）：基于纳米金光纤表面等离子体技术的甲状旁腺激素快速检测试剂盒研发，安徽省高等学校自然科学研究重大项目（批准号：KJ2020ZD13），20万元，正在进行。

1. Shu Zhou^#,*, Maosen Ruan^#, Yunyan Li, Jing Yang, Suwen Bai, Christian Richter, Harald Schwalbe, Can Xie, Bing Shen*（共同通讯）, Junfeng Wang^*. Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide. Cell Research. 2021 Jul; 31(7): 821-824. doi: 10.1038/s41422-020-00452-y. (IF=46.297).

2. Lau On-Chai^#, Shen Bing^#（共同第一）, Wong Ching-On^#, Tjong Yung-Wui, Lo Chun-Yin, Wang Hui-Chuan, Huang Yu, Yung Wing-Ho, Chen Yang-Chao, Fung Man-Lung, Rudd John Anthony, Yao Xiao-Qiang*. TRPC5 channels participate in pressure-sensing in aortic baroreceptor. Nature Communications. 2016 Jul 14; 7: 11947. (IF=12.124)

3. Kwan Hiu-Yee^#, Shen Bing^#（共同第一）, Ma Xin, Kwok Yuk-Chi, Huang Yu, Man Yu-Bun, Yu Shan, Yao Xiao-Qiang*. TRPC1 associates with BK_Ca channel to form a signal complex in vascular smooth muscle cells. Circulation Research. 2009; 104(5): 670-678. (IF=9.214)

4. Yong Wang^#, Suwen Bai^#, Ru Zhang^#, Lin Xia, Linghui Chen, Jizheng Guo, Fang Dai, Juan Du, Bing Shen*（通讯）. Orai3 exacerbates apoptosis of lens epithelial cells by disrupting Ca²⁺ homeostasis in diabetic cataract. Clinical and Translational Medicine. 2021 Mar 04; 11(3): 1-5. Article Number: e327, https://doi.org/10.1002/ctm2.327. (IF=8.554).

5. Linghui Chen, Yanzhuo Chen, Wen Ding, Tao Zhan, Jie Zhu, Lesha Zhang, Han Wang, Bing Shen* （共同通讯）and Yong Wang*. Oxidative stress-induced TRPV2 expression increase involves in diabetic cataract and apoptosis of lens epithelial cells in a high-glucose environment. Cells. 2022 Apr 2; 11(7): 1196. doi: 10.3390/cells11071196. (IF=7.666).

6. Fangfang Xu^#, Jinhang Zhu^#, Ye Chen, Ke He, Jizheng Guo, Suwen Bai, Ying Hu, Ren Zhao, Juan Du, Bing Shen*（通讯）. Physical interaction of tropomyosin 3 and STIM1 regulates vascular smooth muscle contractility and contributes to hypertension. Biomedicine & Pharmacotherapy. 2021 Feb; 134(111126): 1-10. doi: 10.1016/j.biopha.2020.111126. (IF=7.419).

7. Suwen Bai#, Wang Wang#, Li Ye, Lulu Fang, Tao Dong, Rong Zhang, Xin Wang, Huiwen Gao, Bing Shen*（共同通讯）, Shenggang Ding*. IL-17 stimulates neutrophils to release S100A8/A9 to promote lung epithelial cell apoptosis in Mycoplasma pneumoniae–induced pneumonia in children. Biomedicine & Pharmacotherapy. 2021 Sep 22; 143: 112184. doi: 10.1016/j.biopha.2021.112184. (IF=7.419).

8. Tao Dong^#, Ran Yin^#, Qingcai Yu, Wanwei Qiu, Kun Li, Lisheng Qian*, He Li, Bing Shen*（共同通讯）, Guodong Liu*. Sensitive detection of microRNA-21 in cancer cells and human serum with Au@Si nanocomposite and lateral flow assay. Analytica Chimica Acta. 2021 Feb 22; 1147: 56-63. doi: 10.1016/j.aca.2020.12.042. (IF=6.911).

9. Suwen Bai^#, Qianqian Yin^#, Tao Dong, Fang Dai, Ying Qin, Li Ye, Juan Du, Qiu Zhang, Hongbo Chen*, Bing Shen*（共同通讯）. Endothelial progenitor cell–derived exosomes ameliorate endothelial dysfunction in a mouse model of diabetes. Biomedicine & Pharmacotherapy. 2020 Nov; 131: 110756. doi.org/10.1016/j.biopha.2020.110756. (IF=6.529).

10. Yichuan Dai^#, Suwen Bai^#, Chuanzhen Hu, Kaiqin Chu, Bing Shen*（共同通讯）, Zachary J. Smith*. Combined morpho-chemical profiling of individual extracellular vesicles and functional nanoparticles without labels. Analytical Chemistry. 2020 Apr 7; 92(7): 5585-5594. https://doi.org/10.1021/acs.analchem.0c00607. (IF=6.35).

11. Wan Jiang^#, Wei Hu^#, Li Ye, Yanghua Tian, Ren Zhao, Juan Du, Bing Shen*（共同通讯）, Kai Wang*. Contribution of apelin-17 to collateral circulation following cerebral ischemic stroke. Translational Stroke Research. 2019 Jun; 10(3): 298-307. doi: 10.1007/s12975-018-0638-7. (IF=5.847).

12. Guo J^#, Li J^#, Xia L^#, Wang Y, Zhu J, Du J, Lu Y, Liu G, Yao X*, Shen B*（共同通讯）. Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis. Cells. 2020 Feb 26; 9(3). pii: E547. doi: 10.3390/cells9030547. (IF=5.656)

13. Junhao Huang^#,*, Jingwen Liao^#, Yang Fang^#, Hailin Deng, Honggang Yin, Bing Shen*（共同通讯）, Min Hu*. Six-week exercise training with dietary restriction improves central hemodynamics associated with altered gut microbiota in adolescents with obesity. Frontiers in Endocrinology. 2020 Dec 07; 11: 1-10. Article ID 569085. doi: 10.3389/fendo.2020.569085. (IF=5.555).

14. Ma Yan, Zhang Peng, Li Jie, Lu Jun, Ge Jian-Jun, Zhao Zhi-Wei, Ma Xin, Wan Song, Yao Xiao-Qiang*, Shen Bing*（共同通讯）. Epoxyeicosatrienoic acids act through TRPV4-TRPC1-KCa1.1 complex to induce smooth muscle membrane hyperpolarization and relaxation in human internal mammary arteries. Biochimica et Biophysica Acta-Molecular Basis of Disease. 2015 Mar; 1852(3): 552-559. (IF=5.158).

15. Jizheng Guo^#, Ren Zhao^#, Muyao Zhou^#, Jie Li^#, Xiaoqiang Yao, Juan Du, Jiexia Chen*, Bing Shen*（共同通讯）. TRPP2 and STIM1 form a microdomain to regulate store-operated Ca²⁺ entry and blood vessel tone. Cell Communication and Signaling. 2020 Aug 31; 18(1): 138. doi: 10.1186/s12964-020-00560-7. (IF=5.111).

16. Wu Kai-Le^#, Shen Bing^#（共同第一）, Jiang Fei-Fei^#, Xia Lin, Fan Tao-Tao, Qin Mao-Lin, Yang Lian-Qiang, Guo Ji-Zheng, Li Yi-Fan, Zhu Min, Du Juan, Liu Ye-Hai*. TRPP2 enhances metastasis by regulating epithelial-mesenchymal transition in laryngeal squamous cell carcinoma. Cellular Physiology and Biochemistry. 2016, 39: 2203-2215. (IF=5.104).

17. Shen Bing, Cheng Kwong-Tai, Leung Yuk-Ki, Kwok Yuk-Chi, Kwan Hiu-Yee, Wong Ching-On, Chen Zhen-Yu, Huang Yu, Yao Xiao-Qiang*. Epinephrine-induced Ca(2+) influx in vascular endothelial cells is mediated by CNGA2 channels. Journal of Molecular and Cellular Cardiology. 2008; 45(3): 437-445. (IF=5.054).

18. He Li^#, Yansong Xu^#, Xin Zhou, Taiyang Jin, Ziru Wang, Yuansong Sun, Haiping Wang, Datong Jiang, Chunlin Yin, Bing Shen*（共同通讯）, Kai Song*. DIA-based proteomic analysis of plasma protein profiles in pa-tients with severe acute pancreatitis. Molecules. 2022 Jun 17; 27(12): 3880. doi: 10.3390/molecules27123880. (IF=4.927).

19. Shen Bing, Kwan Hiu-Yee, Ma Xin, Wong Ching-On, Du Juan, Huang Yu, Yao Xiao-Qiang*. Cyclic AMP activates TRPC6 channels via PI3K-PKB-MEK-ERK1/2 signaling pathway. Journal of Biological Chemistry. 2011; 286(22): 19439-19445. (IF=4.773).

20. Fang Dai^#, Jizheng Guo^#, Yang Wang, Tian Jiang, Hongbo Chen, Ying Hu, Juan Du, Yan Wang, Xianming Xia, Qiu Zhang*, Bing Shen*（共同通讯）. Enhanced store-operated Ca²⁺ signal of small intestinal smooth muscle cells accelerates small bowel transit speed in type 1 diabetic mouse. Frontiers in Physiology. 2021 Oct 20; 12:691867. doi: 10.3389/fphys.2021.691867. eCollection 2021. (IF=4.755).

1.杨丹，李祥，沈兵，姚晓强. 调节细胞膜电位的方法. 授权公告日：2014.08.27, 中国, 专利号: ZL 200880127474.5.

2. 沈兵，杜鹃，范礼斌，柯道平，朱金行. 一种具有自组装钾通道功能的多肽及其应用. 授权公告日：2013.03.27, 中国, 专利号: ZL 201110091437.7.

3. Li X, Yang D, Shen B, Yao XQ. Method of Modulating Membrane Potential of a Cell. U.S. Non-provisional Patent Application (No. 12/337,642), filed on Dec. 18, 2008.

1. 2019年，沈兵，杜鹃，钟明奎，朱金行. 获得安徽省科学技术奖，三等奖，获奖名称：离子通道病理生理功能研究，排名第一。

2. 杜鹃 沈兵 汪思应 胡金兰，强化学科竞赛教学引领、促进创新医学人才培养，（编号：2016jxcgj121 ），安徽省教学成果奖（竞赛类）三等奖。

3. 2017年被评为安徽医科大学优秀研究生导师。

4. 2017-2018学年，被评为第一临床学院优秀科研启蒙导师。