教授，硕士生、博士生导师，安徽医科大学基础医学院生理学教研室主任。入选教育部跨世纪优秀人才支持计划,安徽省学术技术带头人后备人选, 安徽医科大学生理学教研室学科带头人。中国科学院神经科学研究所博士，2009-2010年美国Northeathern Ohio Universities Colleges of Medicine and Pharmacy 访问教授。获安徽省科学技术奖二等奖、安徽省青年科技奖和中国生理学会张锡钧基金会全国青年优秀生理学论文奖一等奖各一项。主持国家自然科学基金4项，教育部基金2项，省厅级课题3项，在Nature Neuroscience、Journal of Neuroscience、Current Biology等杂志发表SCI收录论文40余篇。 国际期刊Frontiers in Neuroscience杂志客座主编；European Journal of Pharmacology、Journal of Neurochemistry、Acta Pharmacologica Sinica、Neuroscience Bulletin等杂志审稿专家；中国生理学会、中国睡眠研究会理事；安徽省生理学会理事长；安徽省睡眠研究会副理事长；安徽省神经学会常务理事。

1. 2020年-2023年 下丘脑腹外侧视前区-蓝斑核环路调控睡眠-觉醒行为的神经机制，国家自然科学基金（81971236）。

2. 2016年-2019年 内在光敏视网膜神经节细胞介导的光调节促睡眠中枢（下丘脑腹外侧视前区）的神经环路机制，国家自然科学基金（81571293）。

3. 2016年-2018年 高校领军人才引进培育计划，高校学科(专业)拔尖人才学术资助重点项目（gxbjZD2016034）。

4. 2011年-2013年 大鼠腹外侧视前区腺苷对睡眠-觉醒节律调控的研究，国家自然科学基金（81071075）。

5. 2010年-2012年 腺苷对睡眠-觉醒周期调控的细胞学机制，教育部博士点基金（20093420120004）。

6. 2008年-2011年 安徽医科大学国家杰出青年培育计划（GJJQ-0801）。

7. 2007年-2009年 探索辣椒素对感觉神经元的电压依赖性钙离子通道抑制作用机制，国家自然科学基金（30670694）。

8. 2007年-2009年 在致痫大鼠上研究AMPA 受体、NMDA 受体和 KA 受体的相互作用及其作用机制，新世纪优秀人才支持计划（NCET-06-0557）。

9. 2006年-2007年 中药活性成分对癫痫异常放电的影响，安徽省优秀青年科技基金（06043090）。

10. 2006年-2007年 ATP对痛觉神经元钙离子通道和分泌的调控机制，安徽省教育厅自然科学基金（2006KJ361B）。

11. 2003年-2005年 视前区GABA能神经元在慢波睡眠调节中的作用及其机制深入研究。安徽省教育厅自然科学基金（2003KJ223）。

1. Yue Liang, Wu Shi, Anfeng Xiang, Dandan Hu, Liecheng Wang^CA, Ling Zhang^CA. The NAergic locus coeruleus-ventrolateral preoptic area neural circuit mediates rapid arousal from sleep. Current Biology, 2021.

2. Peng Cao, Changmao Chen, An Liu, Qinghong Shan, Xia Zhu, Chunhui Jia, Xiaoqi Peng, Mingjun Zhang, Zahra Farzinpour, Wenjie Zhou, Haitao Wang, Jiang-Ning Zhou, Xiaoyuan Song, Liecheng Wang, Wenjuan Tao, Changjian Zheng, Yan Zhang, Yu-Qiang Ding, Yan Jin, Lin Xu, Zhi Zhang. Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines. Neuron. 2021.

3. Xu W, Yao Y, Zhu D, Han L, Wang L^CA, Wang Y^CA. Involvement of the BNP/NPR-A/BKCa pathway in rat trigeminal ganglia following chronic constriction injury. Journal of Neurophysiology. 2021 Apr 1;125(4):1139-1145.

4. Chen M, Wu S, Shen B, Fan Q, Zhang R, Zhou Y, Zhang P, Wang L^CA, Zhang L^CA. Activation of the δ opioid receptor relieves cerebral ischemic injury in rats via EGFR transactivation. Life Sciences. 2021, 273, 15 May, 119292.

5. Wu F, Wu S, Gui Q, Tang K, Xu Q, Tao Y, Chen M, Cheng J, Wang L^CA, Zhang L^CA. Blue light insertion at night is involved in sleep and arousal-promoting response delays and depressive-[like] emotion in mice. Bioscience Reports. 2021 Mar 26; 41(3):BSR20204033.

6. Cheng J, Wu F, Zhang M, Ding D, Fan S, Chen G, Zhang J^CA, Wang L^CA.The Interaction between the ventrolateral preoptic nucleus and the tuberomammillary nucleus in regulating the sleep-wakefulness cycle. Frontiers in Neuroscience. 2020, Dec 14;14:615854.

7. Ping-Ping Zhang, Hui-Hui Yao, An-Hui Zha, Xing-Yue Liu, Ke-Yu Fan, Yue Xu, Hui-Yao Yuan, Lei Li, Lie-Cheng Wang^CA. Cellular localization of the fmrp in rat retina. Bioscience Reports. 2020 Jun 26;40(6):BSR20200570. doi: 10.1042/BSR20200570.

8. Chen L, Yang ZL, Cheng J, Zhang PP, Zhang LS, Liu XS^CA, Wang LC^CA. Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABAA receptors. Acta Pharmacologica Sinica. 2019, 40(6):755-761.

9. Cheng J,Huang X,Liang Y,Xue T,Wang L^CA, Bao J^CA. Plasticity of Light-induced Concurrent Glutamatergic and GABAergic Quantal Events in the Suprachiasmatic Nucleus. Journal of Biological Rhythms. 2018, 33(1):65-75.

10. Tian Y, Yang C, Cui Y, Su F, Wang Y, Wang Y, Yuan P, Shang S, Li H, Zhao J, Zhu D, Tang S, Cao P, Liu Y, Wang X, Wang L, Zeng W, Jiang H, Zhao F, Luo M, Xiong W, Qiu Z, Li XY, Zhang C. An Excitatory Neural Assembly Encodes Short-Term Memory in the Prefrontal Cortex. Cell Reports. 2018 Feb 13;22(7):1734-1744.

11. Li Z, You Z, Li M, Pang L, Cheng J, Wang L^CA. Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy. Neurosci Bull.2017, 33(3):273-280.

12. Li Z, Fang F, Wang Y, Wang L^CA. Resveratrol protects CA1 neurons against focal cerebral ischemic reperfusion-induced damage via the ERK-CREB signaling pathway in rats. Pharmacology Biochemistry and Behavior. 2016, 146-147:21-27.

13. Xu W, Zhang J, Wang Y, Wang L, Wang X. Changes in the expression of voltage-gated sodium channels Nav1.3, Nav1.7, Nav1.8, and Nav1.9 in rat trigeminal ganglia following chronic constriction injury. Neuroreport. 2016 Aug 17; 27(12):929-34. 

14. Shang S*, Wang C*, Guo C*, Huang X, Wang L^CA, Zhang C^CA. The formation and extinction of fear memory in tree shrews. Frontiers in Behavioral Neuroscience. 2015, 9:204-211. doi: 10.3389/fnbeh.2015.00204.

15. Zhao R, Zhou MY, Li J, Wang X, Su KL, Hu JC, Ye Y, Zhu JH, Zhang GL, Wang K, Du J, Wang LC^CA, Shen B^CA. Increased TRPP2 expression in vascular smooth muscle cells from high-salt intake hypertensive rats: The crucial role in vascular dysfunction. Molecular Nutrition & Food Research. 2015, 59(2):365-372.

16.  He LL, Zhang QF, Wang LC, Dai JX, Wang CH, Zheng LH, Zhou Z. Muscarinic inhibition of nicotinic transmission in rat sympathetic neurons and adrenal chromaffin cells. Philosophical Transactions of the Royal Society B-Biological Sciences. 2015, 370(1672).

17. Zheng LH, Wang CH, Shang SJ, Zhang XY, Wang YS, Wu QH, Hu MQ, Chai ZY, Wu X, Zheng H, Zhang C, Wang LC^CA, Xiong W^CA, Zhou Z^CA. Real-time endocytosis imaging as a rapid assay of ligand-GPCR binding in single cells. American Journal of Physiology-Cell Physiology. 2013, 5(7):C751-60.

18. Zhang J, Yin D, Wu F, Zhang G, Jiang C, Li Z, Wang L^CA, Wang K^CA. Microinjection of adenosine into the hypothalamic ventrolateral preoptic area enhances wakefulness via the A1 receptor in rats. Neurochemical Research. 2013, Aug; 38(8):1616-1623.

19.  Li Z，Pang L，Fang F，Zhang G，Zhang J，Xie M，Wang L^CA. Resveratrol attenuates brain damage in a rat model of focal cerebral ischemia via up-regulation of hippocampal Bcl-2. Brain Research. 2012, April, 1450(2012): 116-124.

20. Cheng J，Dong J，Cui Y，Wang L，Wu B，Zhang C. Interacting Partners of AMPA-Type Glutamate Receptors. Journal of Molecular Neuroscience. 2012 Oct, 48(2):441-447.

21. Xie YP，Chen B，Sanders P，Guo A，Li Y，Zimmerman K，Wang LC^CA，Weiss RM，Grumbach IM，Anderson ME，Song LS^CA. Sildenafil prevents and reverses transverse-tubule remodeling and Ca²⁺ handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension. 2012，59(2):355-62.

22. Wang LC，Tang ZQ，Lu Y. Synaptic activity-induced Ca(2+) signaling in avian cochlear nucleus magnocellularis neurons. Neuroscience Research. 2012，72: 129-139.

23. Wang Y，Liu A，Lei J，Xie M，Li Z，Wang L^CA. Changes in P2Y purinoreceptor-mediated intracellular calcium signal pathways results in inositol-1，4，5-triphosphate-sensitive calcium stores in rat small trigeminal ganglion neurons. Neural Regeneration Research. 2010，12(5)：906-910.

24.Wu Z，Xu Q，Zhang L，Kong D，Ma R^CA，Wang L^CA. Protective Effect of Resveratrol against Kainate-induced Temporal Lobe Epilepsy in Rats. Neurochem Res. 2009, 34(8): 1393-1400.

25. Huang Q，Zhang L，Tang H，Wang L，Wang Y. Modafinil modulates GABA-activated currents in rat hippocampal pyramidal neurons. Brain Res. 2008，1208:74-78.

26. Wu Zheng，Xu Qi，Qian Ruobing，Yu Feng，Yu Lian，Wang Liecheng^CA，Kong Dehu. Temporal lobe epilepsy animal model established by stereotactic microinjection of kainic acid. Neural regeneration research. Neural Regeneration Research. 2008，3 (4)：436-440.

27. Wang LC，Xiong W，Zheng J，Zhou Y，Zheng H，Zhang C，Zheng LH，Zhu XL，ZQ，Wang LY，Cheng HP，Zhou Z. The timing of endocytosis after activation of a G-protein-coupled receptor in a sensory neuron. Biophysical J，2006，90 (10): 3590-3598.

28. Chen XK，Wang LC，Zhou Y，Cai Q，Prakriya M，Duan KL，Sheng ZH，Lingle C，Zhou Z. Activation of GPCRs modulates quantal size in chromaffin cells through G_bγ and PKC. Nature Neuroscience，2005，8(9): 1160-1168.

29. Chen X，Wang L，Zhou Y，Zheng LH，Zhou Z (2005) "Kiss-and-run" glutamate secretion in cultured and freshly isolated rat hippocampal astrocytes. J Neurosci. 2005，25(40): 9236-9243.

30. Zhang GL，Wang LC，Liu H，Zhang JX. Substance P promotes sleep in the ventrolateral preoptic area of rats. Brain Res. 2004，1028(2): 225-232.

31. Zhang C，Xiong W，Zhen H，Wang L，Lu B，Zhou Z. Calcium- and dynamin-independent endocytosis in dorsal root ganglia neurons. Neuron 2004，42(2): 225-236.

32.  Bao L，Jin S，Zhang C，Wang L，Xu Z，Zhang F，Wang L，Ning F，Cai H，Guan J，Xiao H，Xu D Z，He C，Tomas H，Zhou Z，Zhang X. Activation of delt opioid receptors induces receptor insertion and neuropeptide secretion. Neuron 2003，37(1): 121-133.

33. Song P，Wang L，Wang G，Zhou Z，Zhao Z. Interleukin-2 regulates membrane potentials and calcium channels via μopioid receptors in rat dorsal root ganglion neurons. Neuropharmacology 2002，43(8): 1324-1329.

34. Wang L, Cai Shengrong, Huang Zhenxin, Shao Qinglan, Ma Ruchun. Serotonin receptor subtypes that depolarize guinea pig inferior mesenteric ganglion neurons. Brain Res. 1999，839(1): 23-34.

35. Wang L，Cai S，Huang Z，Shao Q，Ma R. 5-Ht1P receptor-mediated slow depolarization in the neurons of guinea pig inferior mesenteric ganglion. Acta Pharmacol.Sinica 1999 20(6): 505-508.

1. 2018年，安徽省科学技术奖二等奖，排名第三；

2. 2009年，安徽省青年科技奖；

3. 2006年，中国生理学会张锡钧基金会，全国青年优秀生理学论文奖一等奖，受奖人员：王烈成，熊巍, 周专；